A buddy of mine asked a favor of me to share a couple papers he wrote regarding #genetherapy and #HIV #treatments. They are behind a paywall but here is a brief description of what he is writing about:
The authors believe that gene therapies should be made affordable, that development of gene therapy applications already funded by public funds should be licensed to manufacturers at a reasonable price and that less cost-intensive manufacturing technologies should be developed. Gene therapies should also be accessible to patients in developing nations.
Read more at: http://www.nature.com/nbt/journal/v32/n12/full/nbt.3084.html
During the past decade, successful gene therapies for During the past decade, immunodeficiencies were finally brought to the clinic. This was accomplished through new gene therapy vectors and improved procedures for genetic modification of autologous hematopoietic stem cells. For HIV, autologous hematopoietic stem cell (HSC) gene therapy with ‘anti-HIV genes’ promises a functional cure for the disease. However, to develop such a therapy and translate it into a clinical application is rather challenging. The risks and benefits of such a therapy have to be understood, and regulatory hurdles need to be overcome. In this joint paper by academic researchers and regulators, the authors are, therefore, outlining a high level roadmap for the early stage development of HSC gene therapy as a potential functional cure for HIV.
For more, go to: http://www.cell.com/trends/molecular-medicine/abstract/S1471-4914%2814%2900137-3
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